Time-Averaged Conformations of the Inclusion Complexes of Cyclodextrin in Solution

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چکیده

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Preparation, Physicochemical Characterization and In-vitro Dissolution Studies of Diosmin-cyclodextrin Inclusion Complexes

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15 صفحه اول

Preparation, Physicochemical Characterization and In-vitro Dissolution Studies of Diosmin-cyclodextrin Inclusion Complexes

Diosmin, a vascular-protecting agent, is practically insoluble in water, and its oral absorption is limited by its extremely low dissolution rate. In this study, β-cyclodextrin (βCD) and 2-hydroxypropyl-β-cyclodextrin (HPβCD) were obtained to improve the solubility and dissolution rate of diosmin. Phase solubility studies of diosmin with βCD and HPβCD in distilled water were conducted to charac...

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ژورنال

عنوان ژورنال: Polymer Journal

سال: 1981

ISSN: 0032-3896,1349-0540

DOI: 10.1295/polymj.13.171